Biological monitoring for isocyanates

Biological monitoring to assess exposure from use of isocyanates in motor vehicle repair.

OBJECTIVES To develop a method for the measurement of a metabolite of hexamethylene diisocyanate (HDI), an isocyanate, and use it to assess the exposure of sprayers employed in motor vehicle repair shops. METHODS Urine samples were taken from sprayers wearing personal protective equipment and spraying in booths or with local exhaust ventilation, from bystanders, and from unexposed subjects. S...

Monitoring , biological

BIOLOGICAL MONITORING OF MERCURY EXPOSURE IN DENTISTS OF TEHRAN

In order to assess the risk for mercury poisoning in dentists, urine specimens were collected and analysed from 250 dentists (190 male, 60 female). Subject data and pertinent health symptoms were asked via a questionnaire. The results indicate that the mean and standard deviation of mercury values were 51.3± 38.0 µg/L, while 27.2 percent of dentists had levels within normal limits (0-19 µg/...

Drug-Encoded Biomarkers for Monitoring Biological Therapies

Blood tests are necessary, easy-to-perform and low-cost alternatives for monitoring of oncolytic virotherapy and other biological therapies in translational research. Here we assessed three candidate proteins with the potential to be used as biomarkers in biological fluids: two glucuronidases from E. coli (GusA) and Staphylococcus sp. RLH1 (GusPlus), and the luciferase from Gaussia princeps (GL...

Biological Monitoring Guidance Values